University of Illinois - Department of Animal Sciences

: ::Mammalian NutriPhysioGenomics:: :



Abstracts

2009

ADSA-CSAS-ASAS Joint Annual Meeting

Invited paper: Molecular adaptations in transition dairy cows. 2009. J. J. LoorJournal of Dairy Science, 92(E-Suppl. 1):486.

Dairy cow adipose depot transcriptomics: effect of level of energy and/or inflammatory challenge

Bovine adipose tissue depot inflammatory gene expression responsiveness to lipopolysaccharide (LPS) in vitro. 2009. M. Mukesh, D. Graugnard, M. Bionaz, J. K. Drackley, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):195.

Changes in deposition of visceral adipose tissues and expression of lipogenesis-related genes induced by diets with different energy levels in non-lactating cows. 2009. P. Ji, J. J. Loor, A. Nikkhah, M. Bionaz, N. A. Janovick, and J. K. Drackley.  Journal of Dairy Science, 92(E-Suppl. 1):120.

Transcriptional adaptations in mesenteric and subcutaneous adipose tissue from non-lactating cows in response to plane of dietary energy. 2009. M. Mukesh, J. K. Drackley, P. Ji, M. Bionaz, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):700.

Overfeeding energy prepartum dramatically affects peripartal expression of mRNA transcripts in subcutaneous adipose tissue compared with controlling energy intake prepartum. 2009. N. Janovick, J. J. Loor, P. Ji, M. Bionaz, R. E. Everts, H. A. Lewin, S. L. Rodriguez-Zas, and J. K. Drackley.  Journal of Dairy Science, 92(E-Suppl. 1):709.

Bovine mammary tissue or mammary cell transcriptomics studies

Mammary transcriptomics response to milk fat-depressing or milk fat-enhancing diets in lactating dairy cows. 2009. G. Invernizzi, B. J. Thering, D. Graugnard, P. Piantoni, M. A. McGuire, G. Savoini, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):117.

Palmitate affects larger gene networks in MACT cells compared with trans-10,cis-12-CLA or PPAR-gamma activation via Rosiglitazone. 2009. G. Invernizzi, A. Kadegowda, M. Bionaz, G. Savoini, R. E. Everts, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):321.

Transcriptomics comparison of MacT cells and mammary tissue during pregnancy and lactation. 2009. R. Sharma, M. Bionaz, A. Kadegowda, R. E. Everts, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):M145.

In vitro culture and characterization of a mammary epithelial cell line from Chinese Holstein dairy cows. 2009. H. Hu, D. P. Bu, J. Q. Wang, Q. Chen, X. Y. Li, H. Y. Wei, L. Y. Zhou, and J. J. LoorJournal of Dairy Science, 92(E-Suppl. 1):M144.

Bovine liver and mammary tissue transcriptomics in response to prepartum dietary energy level and postpartum lipopolysacharide challenge: NRI-USDA project 2007-35204-17758 (2006-2009)

Mammary transcript profiles due to prepartum dietary energy level and bacterial lipopolysacharide challenge in dairy cows early postpartum. 2009. D. Graugnard, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, J. K. Drackley, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):551.

Liver transcript profiles due to prepartum dietary energy level and bacterial lipopolysacharide challenge in dairy cows early postpartum. 2009. D. Graugnard, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, J. K. Drackley, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):690.

Nutritional regulation of skeletal muscle transcriptomics in early-weaned cattle

Dietary starch eff ects on metabolic gene networks in longissimus lumborum of early–weaned angus steers. 2009. D. Graugnard, L. L. Berger, D. B. Faulkner, and J. J. Loor.  Journal of Dairy Science, 92(E-Suppl. 1):305.

2008

ADSA-ASAS Joint Annual Meeting

ASAS Centennial presentation: Lactation biology for the 21st century. 2008. J. J. Loor, and W. Cohick.  Journal of Dairy Science, 91(E-Suppl. 1):553.

Dry cow nutrition, immune function and energy balance, and cell system studies

Moderate excesses of dietary energy markedly increase visceral adipose tissue mass in non-lactating dairy cows. 2008. A. Nikkhah, J. J. Loor, R. L. Wallace, D. Graugnard, J. Vasquez, B. Richards, and J. K. Drackley.  Journal of Dairy Science, 91(E-Suppl. 1):LB4.

Negative energy balance (NEB) alters neutrophil (PMN) gene expression in response to a Streptococcus uberis (S. uberis) mastitis challenge in lactating dairy cows. 2008. K. M. Moyes, J. K. Drackley, D. E. Morin, R. E. Everts, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):T8.

Madin-Darby Bovine Kidney (MDBK) cells and liver tissue of periparturient cows share remarkable similarity in gene expression profiles. 2008. M. Bionaz, R. E. Everts, H. A. Lewin, J. K. Drackley, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):T178.

Periparturient liver and mammary tissue-explant gene expression is responsive to bacterial lipopolysaccharide (LPS) in vitro: A model to study tissue-specifi c genomic responses to infection. 2008. M. Mukesh, D. E. Graugnard, M. Bionaz, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):606.

Neutrophil function in response to level of dietary energy pre-partum and post-partum inflammatory challenge in dairy cows. 2008. D. E. Graugnard, M. Bionaz, M. Mukesh, K. M. Moyes, J. L. Salak-Johnson, J. K. Drackley, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):609.

Nutritional regulation of milk fat synthesis using in vivo and in vitro systems

Effect of abomasal infusion of butterfat, long chain fatty acids or CLA on milk fatty acid composition and mammary tissue lipogenic gene expression in lactating cows. 2008. A. K. G. Kadegowda, J. J. Loor, L. S. Piperova, P. Delmonte, and R. A. Erdman.  Journal of Dairy Science, 91(E-Suppl. 1):T102.

Identification of internal controls for quantitative PCR in mammary tissue from lactating cows receiving various lipid supplements. 2008. A. K. G. Kadegowda, M. Bionaz, B. Thering, L. S. Piperova, R. A. Erdman, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):TH103.

Gene network analysis in mammary tissue of lactating cows receiving abomasal infusions of butterfat, long-chain fatty acids, or CLA. 2008. A. K. G. Kadegowda, L. S. Piperova, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, R. A. Erdman, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):TH104.

Gene network analysis in mammary and liver tissue of lactating mice fed trans10, cis12-CLA. 2008. A. K. G. Kadegowda, A. Thatcher, L. S. Piperova, S. L. Rodriguez-Zas, R. A. Erdman, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):555.

Lipogenic gene expression in MAC-T cells is affected differently by fatty acids and enhanced by PPAR-gamma activation. 2008. A. K. G. Kadegowda, M. Bionaz, L. S. Piperova, R. A. Erdman, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):678.

PPAR-gamma activation and trans-10, cis-12-CLA affect gene expression profi les and intracellular lipid droplet formation and secretion to different extents in MAC-T cells. 2008. A. K. G. Kadegowda, M. Bionaz, R. E. Everts, H. A. Lewin, L. S. Piperova, R. A. Erdman, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):681.

Nutritional regulation of skeletal muscle transcriptomics in early-weaned beef cattle

Metabolic gene networks in longissimus muscle of early-weaned Angus and Angus × Simmental steers fed high-grain or highbyproduct diets during the growing phase. 2008. D. Graugnard, P. Piantoni, M. Bionaz, L. L. Berger, D. B. Faulkner, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):278.

Functional genomics of the mammary gland during pregnancy, lactation, and involution

Comparative MammOmics™ of milk fat synthesis in Mus musculus vs. Bos taurus. 2008. M. Bionaz, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):679.

MammOmics™ in Sus scrofa: Uncovering genomic adaptations underlying mammary development during pregnancy and lactation. 2008. S. Tramontana, W. L. Hurley, M. Bionaz, A. Sharma, D. E. Graugnard, E. A. Cutler, R. E. Everts, P. Ajmone-Marsan, S. L. Rodriguez-Zas, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):683.

Defining gene networks during involution of the mammary gland in dairy cows. 2008. P. Piantoni, W. L. Hurley, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 91(E-Suppl. 1):819.

2007

ADSA-PSA-ASAS-AMPA Joint Annual Meeting

Temporal longissimus muscle gene expression profiles due to plane of dietary energy in early-weaned Angus steers. 2007. D. Graugnard, S. L. Rodriguez-Zas, D. B. Faulkner, L. L. Berger, R. E. Everts, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 90(Suppl. 1):540.

Transcript profiling in mammary of ovariectomized pregnant gilts receiving progesterone and relaxin replacement therapy in late gestation. 2007. D. Graugnard, J. J. Loor, E. A. Cutler, R. E. Everts, S. L. Rodriguez-Zas, and W. L. Hurley. Journal of Dairy Science, 90(Suppl. 1):W235.

Alterations in hepatic gene expression profiles in dairy cows in response to L-carnitine and feed restriction. 2007. D. B. Carlson, J. K. Drackley, M. Bionaz, S. L. Rodriguez-Zas, N. A. Janovick Guretzky, R. E. Everts, H. A. Lewin, and J. J. Loor. Journal of Dairy Science, 90(Suppl. 1):M258.

Prepubertal nutrition effects on bovine mammary parenchyma and fat pad gene expression profiles. 2007. P. Piantoni, D. Graugnard, K. M. Daniels, R. E. Everts, S. L. Rodriguez-Zas, H. A. Lewin, R. M. Akers, and J. J. Loor.  Journal of Dairy Science, 90(Suppl. 1):269.

Palmitate and CLA isomer effects on gene expression in MDBK cells. 2007. B. Thering, M. Bionaz, and J. J. Loor. Journal of Dairy Science, 90(Suppl. 1):M252.

Transcriptional regulation of mammary and adipose tissue gene expression in dairy cows fed a milk fat-depressing or milk fat-enhancing diet. 2007. B. Thering, D. Graugnard, P. Piantoni, R. L. Wallace, R. E. Everts, S. L. Rodriguez-Zas, H. A. Lewin, and J. J. Loor. Journal of Dairy Science, 90 (Suppl. 1):M253.

Effects of energy balance and Streptococcus uberis intrammamary infection challenge on gene expression profiles in bovine mammary tissue. 2007. K. M. Moyes, J. K. Drackley, D. E. Morin, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, and J. J. Loor. Journal of Dairy Science, 90(Suppl. 1):389.

The effect of negative energy balance on immune response to Streptococcus uberis mastitis challenge in mid-lactation dairy cattle. 2007. K. M. Moyes, J. K. Drackley, D. E. Morin, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, and J. J. Loor. Journal of Dairy Science, 90(Suppl. 1):390.

Uncovering adaptive hepatic gene networks due to prepartum plane of dietary energy and physiological state in periparturient Holstein cows. 2007. M. Bionaz, J. K. Drackley, S. L. Rodriguez-Zas, H. M. Dann, N. A. Janovick Guretzky, R. E. Everts, R. Oliveira, H. A. Lewin, and J. J. Loor.  Journal of Dairy Science, 90(Suppl. 1):971.

Liver fatty acid binding protein (FABP) and acyl-CoA synthase (ACSL) isoform gene expression due to plane of dietary energy prepartum in dairy cows. 2007. M. Bionaz, J. K. Drackley, H. M. Dann, and J. J. Loor.  Journal of Dairy Science, 90(Suppl. 1):972.

Altered liver gene expression and reproductive function in postpartum suckled beef cows on different planes of nutrition. 2007. M. Bionaz, F. Samadi, M. J. D'Occhio, and J. J. Loor.  Journal of Dairy Science, 90(Suppl. 1):887.

MammOmics: transcript profiling of the mammary gland during the lactation cycle in Holstein cows. 2007. M. Bionaz, S. L. Rodriguez-Zas, R. E. Everts, H. A. Lewin, and J. J. Loor. Journal of Dairy Science, 90(Suppl. 1):272.

Experimental Biology

Gene networks regulating lipid synthesis in the bovine mammary gland during the lactation cycle. 2007. M. Bionaz, and J. J. Loor. FASEB J 21:855.5

mTOR, AMPK, and insulin receptor signalling networks in the bovine mammary gland during the lactation cycle. 2007. M. Bionaz, and J. J. Loor. FASEB J 21:855.18.

LPIN1-, PPAR-, and SREBF-responsive gene networks regulate mammary lipid synthesis during diet-induced milk fat depression. 2007. M. Bionaz, L. Piperova, R. A. Erdman, and J. J. Loor. FASEB J 21:855.6

Prepartum plane of dietary energy alters hepatic expression of inflammatory and fatty acid oxidation genes in dairy cows. 2007. N. A. Janovick-Guretzky, H. M. Dann, J. J. Loor, and J. K. Drackley. FASEB J 21:552.3


2006

Comparison of the performance of two-dye microarray platforms to characterize gene expression patterns. 2006. S. L. Rodriguez-Zas, R. E. Everts, B. R. Southey, J. K. Drackley, J. J. Loor, and H. A. Lewin. Journal of Dairy Science, 89(Suppl. 1):in press.


2005

Hepatic gene expression profiling in cows with early postpartum ketosis using a bovine 13,000 oligonucleotide microarray. 2005. J. J. Loor, R. E. Everts, H. M. Dann, D. E. Morin, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley. Journal of Dairy Science, 88(Suppl. 1):195.

Mammary gene expression profiling in cows fed a milk fat-depressing diet using a 13,000 oligonucleotide bovine microarray. J. J. Loor, L. Piperova, R. E. Everts, S. L. Rodriguez-Zas, J. K. Drackley, R. A. Erdman, and H. A. Lewin. Journal of Dairy Science, 88(Suppl. 1):196.


2004

Microarray analysis of hepatic gene expression from dry-off through early lactation in dairy cows fed at two intakes during the dry period. 2004. J. J. Loor, N. A. Janovick, H. M. Dann, R. E. Everts, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley.  Journal of Dairy Science, 87(Suppl. 1):T133.    

Mammary and hepatic gene expression analysis in peripartal dairy cows using a bovine cDNA microarray. 2004. J. J. Loor, H. M. Dann, R. E. Everts, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley.  Journal of Dairy Science, 87(Suppl. 1):T134. 

Adipose, mammary, and hepatic gene expression profiling in lactating cows using a bovine cDNA microarray. 2004. J. J. Loor, N. A. Janovick, R. E. Everts, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley.  Journal of Dairy Science, 87(Suppl. 1):T135.

Gene expression profiles in liver of dairy cows in response to feed restriction using a bovine cDNA microarray. 2004. J. J. Loor, D. B. Carlson, R. E. Everts, S. L. Rodriguez-Zas, H. A. Lewin, and J. K. Drackley. Journal of Dairy Science, 87(Suppl. 1):T136.  

Characterization of changes in hepatic expression of inflammation-associated genes during the peripartum period in multiparous Holstein cows using quantitative real time-PCR (RT-PCR). 2004. N. A. Janovick, J. J. Loor, H. M. Dann, H. A. Lewin, and J. K. Drackley. Journal of Dairy Science, 87(Suppl. 1):926.

Application of a random regression model to gene expression profiling. 2004. S. L. Rodriguez-Zas, J. J. Loor, J. K. Drackley, and H. A. Lewin. Journal of Dairy Science, 87(Suppl. 1):365.


Abstracts